THE SCIENCE
What makes MELLOW MOJO work?
(CLICK EACH INGREDIENT TO REVEAL ITS PROPERTIES).
STUDIES SUPPORTING OUR PATENT-PENDING FORMULATIONS
MAGNESIUM CITRATE
“Busy brain” keeping you up? Magnesium is the king of calming nutrients–an NMDA and GABA agonist that soothes and promotes slow-wave sleep.
Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium
supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res
Med Sci. 2012;17(12):1161-1169.
Serefko A, Szopa A, Wlaź P, Nowak G, Radziwoń-Zaleska M, Skalski M, & Poleszak E. Magnesium in depression. Pharmacol Rep. 2013;65(3):547-554.
Hornyak M, Haas P, Veit J, Gann H, & Riemann D. Magnesium Treatment of Primary Alcohol‐Dependent Patients During Subacute Withdrawal: An Open Pilot Study With Polysomnography. Alcohol Clin Exp Res. 2004; 28(11):1702-1709.
VITAMIN D
Suppresses sleep-disrupting inflammation and supports healthy hormone levels, immune function and sleep quality.
Gominak SC, & Stumpf WE. The world epidemic of sleep disorders is linked to vitamin D deficiency.Med hypoth. 2012;79(2):132-135.
ZINC
Deepens those ZZZs by calming glutamate action to promote rest/relaxation.
Gholipour Baradari A, Alipour A, Mahdavi A, Sharifi H, Nouraei SM, Emami Zeydi A.The Effect of Zinc Supplementation on Sleep Quality of ICU Nurses: A Double Blinded Randomized Controlled Trial. Workplace Health Saf. 2018 Apr; 66(4):191-200.
Inositol
Mental noise too loud? Inositol turns the volume down and induces relaxation.
Palatnik A, et al. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment
of panic disorder. J Clin Psychopharmacol. 2001 Jun; 21(3):335-9.
VITAMIN C
Supports healthy levels of stress-fighting hormones/antioxidants so you can mellow out more effectively.
Lira AB, de Sousa Rodrigues CF.Evaluation of oxidative stress markers in obstructive sleep apnea syndrome and additional antioxidant therapy: a review article. Sleep Breath. 2016 Dec;20(4):1155-1160.doi: 10.1007/s11325-016-1367-3.
GLYCINE
Decreases brain excitability and has a cooling effect on body temperature, like sleeping on the cool side of a pillow, but in nutrient form.
Kawai N, Sakai N, Okuro M, Karakawa S, Tsuneyoshi Y, Kawasaki N, Takeda T, Bannai M, Nishino S. The sleep-promoting and hypothermic effects of glycine are mediated by NMDA receptors in the suprachiasmatic nucleus. Neuropsychopharmacology. 2015 May;40(6):1405-16. doi:10.1038/npp.2014.326.
GABA
The brain’s primary “calm down” chemical that catalyzes a soothing, hypnotic effect without inducing morning fog.
Yamatsu A, Yamashita Y, Maru I, Yang J, Tatsuzaki J, Kim M.The Improvement of Sleep by Oral Intake
of GABA and Apocynum venetum Leaf Extract. J Nutr Sci Vitaminol (Tokyo). 2015;61(2):182-7. doi:
10.3177/jnsv.61.182.
VITAMIN E
Extinguishes the oxidation and inflammation that causes poor sleep quality.
Parazzini F. Resveratrol, tryptophanum, glycine and vitamin E: a nutraceutical approach to sleep
disturbance and irritability in peri- and post-menopause. Minerva Ginecol. 2015 Feb;67(1):1-5. Review.
5-HTP
A tranquil, anti-anxiety hormone precursor that converts into melatonin, the body’s master sleep hormone.
Realini R, Mascetti R. L-5-HTP in the treatment of sleep disorders in patients with depression and
anxiety states].Schweiz Rundsch Med Prax. 1988 Aug 23; 77(34A):24-7.
MELATONIN
Melatonin (M): The hormone with the strongest knockout punch in a dosage that will not induce dependency.
Claustrat B, Leston J. Melatonin: Physiological effects in humans. Neurochirurgie. 2015 Apr-Jun;61(2-3):77-84. doi: 10.1016/j.neuchi.2015.03.002.
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